Title
Direct mechanical measurement of single DNA molecules through an optical microscope
Date Issued
01 December 1993
Access level
metadata only access
Resource Type
conference paper
Author(s)
Universidad de Oregon
Publisher(s)
Publ by San Francisco Press Inc
Abstract
The article presents an investigation on the single DNA 'molecules' elastic properties. An optical microscope was used to observe the equilibrium positions of the beads while being acted upon by magnetic and hydrodynamic forces. The freely-jointed chain model showed that DNA has local curvature which needs more energy for straightening. The effect of bend inducing CIS-diammine dichloro platinum (DDP) is large and supports the hypothesis of natural curvature in DNA.
Start page
86
End page
87
Language
English
OCDE Knowledge area
Química física Física atómica, molecular y química
Scopus EID
2-s2.0-0027705538
Source
Proceedings - Annual Meeting, Microscopy Society of America
ISSN of the container
04248201
Conference
Proceedings of the 51st Annual Meeting Microscopy Society of America
Sources of information: Directorio de Producción Científica Scopus